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The study is a prospective registry but it is necessary to have an upstream quality control with a certified reader from each center. A multicenter study is like a fish soup. The more the fish or contributing centers, the tastier is the soup, but a single rotten fish will render the entire soup uneatable. Therefore, a mandatory quality control is required.
For each step you have 3 possible attempts. For each clip, you have 4 possible answers. If you reach a concordance of ≥80% with the gold standard of unanimous expert reading you are certified. The test is specific for each step: step A (regional wall motion); step B (B-lines); step C (left ventricular volume changes); step D (coronary flow velocity reserve); step F (mitral regurgitation); step L (left atrium volume changes); step P (pulmonary artery systolic pressures) and so on.
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